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Viral conjunctivitis in children: the specific clinical features and treatment

Abstract

DOI: 10.32364/2311-7729-2022-22-3-191-196

N.V. Kazinskaya, V.Yu. Evgraphov, I.A. Il’inskaya

Pirogov Russian National Research Medical University, Moscow, Russian Federation

Over the last few years, viral conjunctivitis in children has become a significant challenge. Modern diagnostic techniques facilitate a prompt detection of this disease, assuming that a qualified approach is used by the ophthalmologist for making diagnosis in such cases. As a broad spectrum of drugs is available for the treatment of inflammation of the anterior eye segment, the ophthalmologist can customize medications for each patient with viral conjunctivitis. The key problem of pediatric ophthalmology is associated with the age limits for choosing eye drops and ointments. Besides, most cases of viral conjunctivitis in children occur amid infection of the upper respiratory tract, requiring a comprehensive approach to the management of this health condition. The article describes the most common types of child’s conjunctivitis and provides authors’ own findings for 195 patients, 0–18 years old, including the specific clinical features and the conside rations for treatment. In addition, a clinical case report is presented where an incorrect interpretation of symptoms of the anterior eye segment inflammation has led to the inappropriate medication administration and the development of such complications as keratitis and reduced visual acuity. In general, timely diagnosis of the disease and adequate treatment of pediatric patients, in contrast to adults, ensures an uncomplicated clinical outcome, without scarring, uveitis or residual infiltrates.

Keywords: viral conjunctivitis, keratitis, adenovirus, herpes, ocular mucous membrane, interferon, para-aminobenzoic acid.

For citation: Kazinskaya N.V., Evgraphov V.Yu., Il’inskaya I.A. Viral conjunctivitis in children: the specific clinical features and treatment. Russian Journal of Clinical Ophthalmology. 2022;22(3):191–196 (in Russ.). DOI: 10.32364/2311-7729-2022-22-3-191-196.

Вирусные конъюнктивиты у детей: особенности течения и лечения

About the authors:

Natal’ya V. Kazinskaya — C. Sc. (Med.), associate professor of the Department of Ophthalmology, Pirogov Russian National Research Medical University; 1, Ostrovityanov str., Moscow, 117437, Russian Federation; ORCID iD 0000-0002-8428-827X.

Vladimir Yu. Evgrafov — Dr. Sc. (Med.), Professor of the Department of Ophthalmology, Pirogov Russian National Research Medical University; 1, Ostrovityanov str., Moscow, 117437, Russian Federation; ORCID iD 0000-0001-7903-450Х.

Irina A. Il´inskaya — C. Sc. (Med.), assistant of the Department of Ophthalmology, Pirogov Russian National Research Medical University; 1, Ostrovityanov str., Moscow, 117437, Russian Federation; ORCID iD 0000-0002-2921-9781.

Contact information: Natal’ya V. Kazinskaya, e-mail: nkazinskaya@mail.ru.

Financial Disclosure: no authors have a financial or property interest in any material or method mentioned.

There is no conflict of interests.

Received 25.05.2022.

Revised 20.06.2022.

Accepted 13.07.2022.

References
1. Clinical guidelines. Conjunctivitis. 2021. (Electronic resource.) URL: https://cr.minzdrav.gov.ru/schema/629_1 (access date: 05.12.2022) (in Russ.).
2. Maychuk D.Yu., Maychuk Yu.F. Ophtalmoferon® — 15 years of widespread use in the treatment and prevention of infectious eye diseases. Infectious diseases: News, Opinions, Training. 2017;1(18):82–100 (in Russ.). DOI: 10.24411/2305-3496-2017-00027.
3. Hoyt K.S., Taylor D. Neonatal conjunctivitis. In: Hoyt K.S., Taylor D. Pediatric ophthalmology. Translated from English, E.I. Sidorenko ed. M.: Publishing house Panfilov. 2015. Vol. 1: 104–108 (in Russ.).
4. Shabalov N.P. Neonatology: textbook. Moscow: GEOTAR-Media; 2016. Vol. 2 (in Russ.).
5. Saydasheva E.I., Malinovskaya N.A., Panchishena V.M. Infectious and inflammatory diseases of the eye and its adnexa in neonatal age: textbook. St. Petersburg: Publishing House of SZGMU im. I.I. Mechnikov; 2018 (in Russ.).
6. Dart J.R.G., Wilkins M. External eye disease and the oculocutaneous disorders. In: Lambert S.R., Lyons C.J. Taylor and Hoyt’s Pediatric Ophthalmology and Strabismus. 2005.
7. Uchaikin V.F., Nisevich N.I., Shamsheva O.V. Children Infectious Diseases: a textbook. M.: GEOTAR-Medica; 2011 (in Russ.).
8. Alexeev V.N., Martynova E.B., Zhukova E.A. Pathogenically based treatment of adenoviral eye diseases. RMJ. Clinical ophthalmology. 2005;4:146 (in Russ.).
9. Trufanov S.V., Malozhen S.A., Krakhmaleva D.A., Pivin E.A. Adenovirus epidemic keratoconjunctivitis. RMJ. Clinical ophthalmology. 2016;3:144–150 (in Russ.).
10. Aoki A., Isobe K., Ohno S. Nationwide surveillance program of epidemic conjunctivitis in Japan. In: Bialasiewicz A.A., Schaal K.P. eds. Infectious diseases of the eye. Philadelphia: Butterworth-Heinemann; 1994:309–316.
11. D’Angelo L.J., Hierholzer J.C., Holman R.C., Smith J.D. Epidemic keratoconjunctivitis caused by adenovirus type 8: epidemiologic and laboratory aspects of a large outbreak. Am J Epidemiol. 1981;113:44–49. DOI: 10.1093/oxfordjournals.aje.a113064.
12. Vorobyeva I. The role of Ophthalmoferon in the treatment of viral eye diseases in type 2 diabetes patients with diabetic retinopathy (literature review). Vrach. 2018;29(10):25–30. DOI: 10.29296/25877305-2018-10-07.
13. Astasheva I.B. Features of the clinical course, observation and prevention of adenoviral epidemic keratoconjunctivitis in infant in the perinatal center. Detskie Infektsii. 2017;16(4):22–25 (in Russ.). DOI: 10.22627/2072-8107-2017-1 6-4-22-25.
14. Sheikh A., Hurwitz B., van Schayck C.P. et al. Antibiotics versus placebo for acute bacterial conjunctivitis. Antibiotics versus placebo for acute bacterial conjunctivitis. Cochrane Database Syst Rev. 2012;(9):CD001211. DOI: 10.1002/14651858.CD001211.pub3.
15. Sidorenko E.I., Guseva M.R., Astasheva I.B. et al. General principles and methods for laboratory diagnosis of conjunctivitis in children. Russian Ophthalmology of Children. 2016;4:14–31 (in Russ.).
16. Herpes simplex — ocular; NICE CKS, November 2016.
17. Zhang L., Zhao N., Huang X. et al. Molecular epidemiology of acute hemorrhagic conjunctivitis caused by coxsackie A type 24 variant in China, 2004–2014. Sci Rep. 2017;7:45202. DOI: 10.1038/srep45202.
18. Demina A.V., Netesov S.V. Enteroviruses. Part II: enteroviral infections: the variety of clinical implications (review). 2009;6(140):116–125 (in Russ.).
19. Rodríguez-Ares T., Lamas-Francis D., Treviño M. et al. SARS-CoV-2 in Conjunctiva and Tears and Ocular Symptoms of Patients with COVID-19. Vision (Basel). 2021;5(4):51. DOI: 10.3390/vision5040051.
20. Ozturk M., Kumova D., Alacam S. et al. Detection of coronavirus in tear samples of hospitalized patients with COVID-19. Int Ophthalmol. 2022:1–12. DOI: 10.1007/s10792-022-02442-y. Epub ahead of print.
21. Ozturker Z.K. Conjunctivitis as sole symptom of COVID-19: A case report and review of literature. Eur J Ophthalmol. 2021;31(2):NP161–NP166. DOI: 10.1177/1120672120946287.
22. BenEzra D. Blepharitis and Conjunctivitis. Guidelines for diagnosis and treatment. Editorial glosa; 2006.
23. Neroev V.V., Vakhova E.S. Diseases of the conjunctiva. In: Avetisov S.E., Egorov E.A., Moshetova L.K. et al. Ophthalmology: National leadership. Moscow: GEOTAR-Media; 2018 (in Russ.).
24. Maychuk Yu.F. Ophthalmoferon in ophthalmic practice. Oculist. 2006;3:4–6 (in Russ.).
25. Kaufman H.E. Adenovirus advances: new diagnostic and therapeutic options. Curr Opin Ophthalmol. 2011;22(4):290–293. DOI: 10.1097/ICU.0b013e3283477cb5.
26. Bielory L. Allergic diseases of the eye. Med Clin North Am. 2006;90(1):129–148. DOI: 10.1016/j.mcna.2005.08.013.

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