Reparative therapy in patients with exogenous corneal damage
Kadyshev V.V.^{1, 2}, Halluf Z.<sup>1

1</sup> City clinic №210, Moscow
² Research Centre for Medical Genetics, Moscow

Objective. To evaluate the efficacy of corneal protector (Corneregel) in complex treatment of corneal micro damages; to evaluate terms of disability and corneal healing.
Patients and methods. 120 patients with corneal micro damages underwent comprehensive ophthalmic diagnostics ( visual acuity, biomicroscopy, ophthalmic tonometry, fluorescein eye stain test). In case of establishing the diagnosis, ethiopathogenetic and symptomatic therapy was prescribed, including corneal reparative therapy. Patients were divided into two groups. Group I (n= 50) received Dexpanthenol 5% gel (Corneregel). Group II as reparative therapy received deproteinized dialysate (DD) from calf blood. Statistical analysis was performed using STATISTICA 10.0 (U.S.A.StatSoft,).
Results. Statistically significant reduction of corneal reparation terms and disability period was observed in Group I. In Corneregel group the average period of corneal healing was 3,88±0,94 days, in DD gel group - 5,08±1,00 days (t-test = 0,87). 
The similar tendency was revealed in the analysis of disability period - 5,88±0,94 and 7,3±1,05 days, respectively (t-test = 1,01). Pronounced subjective comfort in case of Corneregel application was marked by patients with exogenous corneal damage.
Conclusion. Dexspanthenol eye gel 5% (Corneregel) can be recommended for reparative therapy of cornea to reduce terms of corneal healing and disability. Corneregel can be recommended as an essential remedy of first-aid kit.

Key words. Corneal protector, reparative therapy, Corneregel, microdamage of cornea, dry eye syndrome.

For citation: Kadyshev V.V., Halluf Z. Reparative therapy in patients with exogenous corneal damage // RMJ. Clinical ophthalmology. 2016. № 4. P. 200–203.