The duration of the hypotensive action of anti-glaucoma medicines
Kuroyedov A.V.^1,2, Brezhnev A.Yu.<sup>3

1</sup> Mandryka Central Clinical Hospital, Moscow
² Pirogov Russian National Research Medical University, Moscow
³ Kursk State Medical University

The paper addresses the findings on the possible duration of action of various topical agents and their combinations for glaucoma. The key reasons for gradual reduction of glaucoma medication efficacy are breach of tolerance, pharmacological genetic factors, late diagnosis, comorbidities, poor adherence to treatment, and ocular side effects. Long-term efficacy criteria are stable intraocular pressure and preserved vision (in particular, visual fields). More patients may receive long-term effective treatment than today. We can be confident of this due to the possible and required motivation for clinical check-ups and treatment, active diagnosing and treatment of comorbidities, improved diagnostic equipment and the development of novel (more effective and save) glaucoma medications, pharmacological industry development (as a result, competitive activity increases thus leading to the alternatives and reduced prices), and the development of clear therapeutic algorithms (standards, guidelines etc.).

Key words: glaucoma, medical treatment, duration of action of glaucoma medications, treatment efficacy.

For citation: Kuroyedov A.V., Brezhnev A.Yu. The duration of the hypotensive action of anti-glaucoma medicines // RMJ. Clinical ophthalmology. 2016. № 4. P. 214–219.