DOI: 10.21689/2311–7729–2019–19-1-54-58

Lutein and zeaxanthin complex: ophthalmologists’ choice

A.V. Korneeva
LLC “Three-Z-Moscow”, Moscow, Russian Federation

This article summarizes the data on carotenoids and their role in retinal antioxidant protection. The relevance of lutein and zeaxanthin complexes and criteria for their choice are discussed. Data on the relationship between low carotenoid levels in the fovea and age-related macular degeneration (AMD) are available. There are several lutein and zeaxanthin complexes which formulations were developed according to the AREDS2. Clinical trials demonstrate that lutein and zeaxanthin complexes improve both retinal functional activity and morphological parameters and are effective to prevent AMD development and progression. They are recommended for unbalanced diet, gastrointestinal disorders, psychoemotional stresses (e.g., drivers or professional athletes), intensive ultraviolet (e.g., welders, lighters or mountain tourists), myopia, accommodation cramp, inflammatory and degenerative ocular disorders. Optimal dosing is 1 tablet per day for at least 3 months twice a year.

Key words: lutein, zeaxanthin, carotenoids, antioxidants, age-related macular degeneration.
For citation: Korneeva A.V. Lutein and zeaxanthin complex: ophthalmologists’ choice. Russian Journal of Clinical Ophthalmology. 2019;19(1):54–58.