Experimental models of glaucoma in the research of a new neuroprotection treatment
Alyabyeva Zh.Yu. 1.2, Romanova T.B. 1,
Lipatova V.A. 1, Botchei V.M. 3

1 Pirogov Russian National Research Medical University
2 Moscow Glaucoma Center (City Clinical Hospital 15)
3 Peoples’ Friendship University of Russia

For modelling of glaucoma different chemical and physical agents (hypertonic saline, adrenalin, laser and so on) are used in vivo in experimental animals as well as genetically modified animals such as rats (with the genes responsible for the development of glaucoma. Models, including apoptosis of ganglion retinal cells, astrocytes of the optic nerve head are applied for modelling glaucoma in vitro. The review presents different glaucoma models and their use as well as the directions of the research of the perspective neuroprotection medications.

Key words: glaucoma model, neuroprotection, experiment.

For citation: Alyabyeva Zh.Yu., Romanova T.B., Lipatova V.A., Botchei V.M. Experimental models of glaucoma in the research of a new neuroprotection treatment. // RMJ. Clinical ophthalomology. 2015. № 2. P. 145–149.