Sustainable pharmacological relief of headache

E.G. Filatova 

I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow 

Tension-type headache (TTH) and migraine are the most common types of headache. They can have a significant impact on the ability to work and life quality. Sustainable pharmacological relief of these headache types is still an important task and involves not only the choice of an adequate mechanism of action and drug intensity, but also the assessment of individual factors concerning drug safety. It has been shown that the combination of ibuprofen with pitofenone and fenpiverinium bromide predominates in efficacy versus ibuprofen mono-preparations in the treatment of TTH. Using a drug with international nonproprietary names for pharmaceutical substances ibuprofen, pitofenone and fenpiverinium bromide in coated tablets reduces the risk of components’ direct effect on the gastric mucosa. The combined drug works well in irregular short-term use on demand, as it has an over-the-counter status and effectively relieves headache.

Keywords: tension-type headache, migraine, combination drug, headache relief, ibuprofen, pitofenone, fenpiverinium bromide.

For citation: Filatova E.G. Sustainable pharmacological relief of headache. RMJ. 2022;5:17–20.