Obese patient: focus on cognitive health

Obese patient: focus on cognitive health

E.V. Ekusheva^1,2, F.Kh. Dzgoeva³, K.P. Tuzhikov¹ 

¹Academy of Postgraduate Education under Federal Research and Clinical Center of the Federal Medical-Biological Agency, Moscow

²Belgorod State University, Belgorod

³National Medical Research Center of Endocrinology, Moscow 

Obesity is a chronic multifactorial disease that has a negative impact on almost all organs and systems in the body and contributes to the occurrence of concomitant diseases and pathological conditions that significantly worsen the life quality of these patients. The majority of obese and overweight patients have cognitive impairments (CI) of varying severity up to dementia, which necessitates their timely diagnosis even before the development of clinical dementia. That is because it allows the use of targeted, pathogenetically based therapy which slows down the current pathological process, and in some cases significantly affects the further cognitive functioning of patients. The article presents the data of a multicenter randomized clinical trial on BRAINMAX^® with the inclusion of young and middle-aged patients, the use of which led to a significant improvement in cognitive performance (concentration and vigilance, working memory, volume and speed of attention switch, information processing speed and executive functions), a decrease in the severity of asthenic manifestations and an improvement in the life quality, while a better effect was observed after 2 courses of the studied preparation. The data obtained allowed to recommend the use of BRAINMAX^® for the treatment of CI in obese and overweight patients to reduce the severity of existing CIs and improve their life quality.

Keywords: obesity, overweight, cognitive impairment, non-dementia disorders, therapy of cognitive impairment.

For citation: Ekusheva E.V., Dzgoeva F.Kh., Tuzhikov K.P. Obese patient: focus on cognitive health. RMJ. 2023;3:21–24.