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Cognitive impairment in patients 
with chronic pain syndrome

Abstract

DOI: 10.32364/2587-6821-2020-4-9-573-577

E.V. Ekusheva

Academy of Postgraduate Education under Federal Research Clinical Center of the Federal Medical-Biological Agency, Moscow, Russian Federation

Belgorod National Research University, Belgorod, Russian Federation

Cognitive impairments and pain syndrome are frequent disorders in the general population and one of the most topical and significant issues of modern medicine faced by doctors of various specialties in clinical practice, both on intpatient and outpatient basis. The article discusses the current understanding of the association and pathogenetic mechanisms concerning cognitive impairment in patients with chronic pain. The most optimal strategies for these patients management are considered, including pharmacological therapy with medication of proven efficacy and various directions of non-drug exposure. The article describes a clinical case of a patient with muscle-tonic and myofascial pain syndromes (6–7 points on VAS scale) and a syndrome of mild cognitive impairment that hindered his professional activity and therefore required therapeutic correction. Correctly selected therapy with the inclusion of analgesics and the nootropic citicoline provided pain relief in the lumbar region, improved concentration and overall well-being.

Keywords: pain syndrome, chronic pain, cognitive impairment, citicoline, choline.

For citation: Ekusheva E.V. Cognitive impairment in patients with chronic pain syndrome. Russian Medical Inquiry. 2020;4(9):573–577. DOI: 10.32364/2587-6821-2020-4-9-573-577.



Acknowledgment

The author and Editorial Board are grateful to LLC Grotex for providing full-text foreign articles required to write the review.

About the author:

Evgeniya V. Ekusheva — Dr. of Sci. (Med.), Professor of the Department of Nervous System Diseases, Academy of Postgraduate Education under Federal Research Clinical Center of the Federal Medical-Biological Agency: 91, Volokolamskoye highway, Moscow, 125371, Russian Federation; Leading Researcher, Belgorod National Research University: 85, Pobedy street, Belgorod, 308015, Russian Federation; ORCID iD 0000-0002-3638-6094.

Contact information: Evgeniya V. Ekusheva, e-mail: ekushevaev@mail.ru. Financial Disclosure: the author has not a financial or property interest in any material or method mentioned. There is no conflict of interests. Received 06.10.2020, revised 20.10.2020, accepted 03.11.2020. 

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