1. Airaksinen O., Brox J.I., Cedraschi C. et al. Chapter 4. European guidelines for the management of chronic nonspecific low back pain. Eur Spine J. 2006;15(Suppl 2):S192–300. DOI: 10.1007/s00586-006-1072-1.
2. Hoy D., Bain C., Williams G. et al. A systematic review of the global prevalence of low back pain. Arthritis Rheum. 2012;64(6):2028–37. DOI: 10.1002/art.34347.
3. Andersson G.B. Epidemiological features of chronic low-back pain. Lancet. 1999;354:581–585. DOI: 10.1016/S0140-6736(99)01312-4.
4. Manchikanti L., Singh V., Falco F.J. E. et al. Epidemiology of low back pain in adults. Neuromodulation 2014;17(Suppl 2):3–10. DOI: 10.1111/ner.12018.
5. Selkirk S.M., Ruff R. Low back pain, radiculopathy. Handb Clin Neurol. 2016;136:1027–1033. DOI: 10.1016/B978-0-444-53486-6.00053-3.
6. GBD 2017 DALYs and HALE Collaborators. Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018;392(10159):1859–1922. DOI: 10.1016/S0140-6736(18)32335-3.
7. Kurushina O.V., Barulin A.E. Back pain: gender characteristics. Saratovskiy nauchno-meditsinskiy zhurnal. 2012;8(2):477–481 (in Russ.).
8. Tretyakova E.A., Karakulova Yu.V. Clinical and biochemical study of the mechanisms of the formation of chronic pain in the lower back. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2011;8:58–61 (in Russ.).
9. Battié M.C., Videman T., Kaprio J. et al. The twin spine study: Contributions to a changing view of disc degeneration. Spine J. 2009;9:47–59. DOI: 10.1016/j.spinee.2008.11.011.
10. Duggleby T., Kumar S. Epidemiology of juvenile low back pain: a review. Disabil Rehabil. 1997;19:505–512.
11. Deyo R.A., Andersson G., Bombardier C. et al. Outcome measures for studying patients with low back pain. Spine. 1994;19:2032S–2036S.
12. Levin O.S. Modern approaches to the diagnosis and treatment of back pain. M.; 2006 (in Russ.).
13. Maroudas A., Stockwell R.A., Nachemson A., Urban J. Factors involved in the nutrition of the human lumbar intervertebral disc: Cellularity and diffusion of glucose in vitro. J Anat. 1975;120:113–130.
14. Barulin A.E., Kurushina O.V., Drushlyakova A.A. et al. Physiological substantiation of the stress-factor component on the formation of static-dynamic disorders. Rossiyskiy zhurnal boli. 2017;1(52):6 (in Russ.).
15. Danilov A.B. Pain management. Biopsychosocial approach. M.: AMM PRESS; 2012 (in Russ.).
16. Deyo R.A., Mirza S.K., Turner J.A., Martin B.I. Overtreating chronic back pain: time to back off? J Am Board Fam Med. 2009;22:62–68. DOI: 10.3122/jabfm.2009.01.080102.
17. Barantsevich E., Andreev V. Possibilities of treating chronic pain in lumbosacral radiculopathy. Vrach. 2012;11:13–19 (in Russ.).
18. Levin O.S. Diagnostics and treatment of neurological manifestations of spinal osteochondrosis. Consilium medicum. 2004;6:547–554 (in Russ.).
19. Kukushkin M.L. Diagnosis and treatment of non-specific back pain. Neurology and Psychiatry. 2012;4:2–6 (in Russ.).
20. Kuhlwein A., Meyer H.J., Koehler C.O. [Reduced diclofenac administration by B vitamins: results of a randomized double-blind study with reduced daily doses of diclofenac (75 mg diclofenac versus 75 mg diclofenac plus B vitamins) in acute lumbar vertebral syndromes]. Klin Wochenschr. 1990;68(2):107–115 (in German).DOI: 10.1007/BF01646857.
21. Brüggemann G., Koehler C.O., Koch E.M. [Results of a double-blind study of diclofenac + vitamin B1, B6, B12 versus diclofenac in patients with acute pain of the lumbar vertebrae. A multicenter study]. Klin Wochenschr. 1990;68(2):116–120.
22. Vetter G., Brüggemann G., Lettko M. et al. Shortening diclofenac therapy by B vitamins. Results of a randomized double-blind study, diclofenac 50 mg versus diclofenac 50 mg plus B vitamins, in painful spinal diseases with degenerative changes. Z Rheumatol. 1988;47(5):351–362.
23. Song X-S., Huang Z-J., Song X-J. Thiamine suppresses thermal hyperalgesia, inhibits hyperexcitability, and lessens alterations of sodium currents in injured, dorsal root ganglion neurons in rats. Anesthesiology 2009;110(2):387–400. DOI: 10.1097/ALN.0b013e3181942f1e.
24. Thériault O., Poulin H., Thomas G.R. et al. Pyridoxal-5’-phosphate (MC-1), a vitamin B6 derivative, inhibits expressed P2X receptors. Can J Physiol Pharmacol. 2014;92(3):189–196.
25. Chiang E-P., Smith D.E., Selhub J. et al. Inflammation causes tissue-specific depletion of vitamin B6. Arthritis Res Ther. 2005;7(6):R1254–1262. DOI: 10.1186/ar1821.
26. Erfanparast A., Tamaddonfard E. Effects of intracortical microinjection of vitamin B12 on penicillin-induced epileptiform activity in rats. Acta Neurobiol Exp (Wars). 2015;75(2):200–207.
27. Hosseinzadeh H., Moallem S.A., Moshiri M. et al. Anti-nociceptive and anti-inflammatory effects of cyanocobalamin (vitamin B12) against acute and chronic pain and inflammation in mice. Arzneimittelforschung. 2012;62(7):324–329. DOI: 10.1055/s-0032-1311635.
28. Moallem S.A., Hosseinzadeh H., Farahi S. A study of acute and chronic anti-nociceptive and anti-inflammatory effects of thiamine in mice. Iran Biomed J. 2008;12(3):173–138.
29. McCarty M.F. High-dose pyridoxine as an "anti-stress" strategy. Med Hypotheses. 2000;54(5):803–807. DOI: 10.1054/mehy.1999.0955.
30. Deng X.-T., Han Y., Liu W.-T., Song X.-J. B Vitamins potentiate acute morphine antinociception and attenuate the development of tolerance to chronic morphine in mice. Pain Med. 2017;18(10):1961–1974. DOI: 10.1093/pm/pnw358.
31. Menezes R.R., Godin A.M., Rodrigues F.F. et al. Thiamine and riboflavin inhibit production of cytokines and increase the anti-inflammatory activity of a corticosteroid in a chronic model of inflammation induced by complete Freund’s adjuvant. Pharmacol Rep 2017;69(5):1036–1043. DOI: 10.1016/j.pharep.2017.04.011.
32. Onk D., Mammadov R., Suleyman B. et al. The effect of thiamine and its metabolites on peripheral neuropathic pain induced by cisplatin in rats. Exp Anim. 2018;67(2):259–269. DOI: 10.1538/expanim.17-0090.
33. Khoromi S., Patsalides A., Parada S. et al. Topiramate in chronic lumbar radicular pain. J Pain. 2005;6(12):829–836. DOI: 10.1016/j.jpain.2005.08.002.
34. Mauro G.L., Martorana U., Cataldo P. et al. Vitamin B12 in low back pain: a randomised, double-blind, placebo-controlled study. Eur Rev Med Pharmacol Sci. 2000;4(3):53–58.
35. Bates C.J., Pentieva K.D., Prentice A. et al. Plasma pyridoxal phosphate and pyridoxic acid and their relationship to plasma homocysteine in a representative sample of British men and women aged 65 years and over. Br J Nutr. 1999;81:191–201.
36. Cattaneo M. Hyperhomocysteinemia: a risk factor for arterial and venous thrombotic disease. Int J Clin Lab Res. 1997;27:139–144.
37. Ridker P.M., Hennekens C.H., Buring J.E., Rifai N. C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N Engl J Med. 2000;342:836–843. DOI: 10.1056/NEJM200003233421202.
38. Chiang E.-P., Smith D.E., Selhub J. et al. Inflammation causes tissue-specific depletion of vitamin B. Arthritis Res. 2005;7:R1254–R1262. DOI: 10.1186/ar1821.
39. Mibielli M.A., Geller M., Cohen J.C. et al. Diclofenac plus B vitamins versus diclofenac monotherapy in lumbago: the DOLOR study. Curr Med Res Opin. 2009;25(11):2589–2599. DOI: 10.3111/13696990903246911.
40. Mimenza Alvarado A., Aguilar Navarro S. Clinical Trial Assessing the Efficacy of Gabapentin Plus B Complex (B1/B12) versus Pregabalin for Treating Painful Diabetic Neuropathy. J Diabetes Res. 2016;2016:4078695. DOI: 10.1155/2016/4078695.
41. Danilov A.B. Treatment of acute back pain: B vitamins or NSAIDs. RMJ. 2010;18(31):35–40 (in Russ.).
42. Stracke H., Hammes H.P., Werkmann D. et al. Efficacy of benfotiamine versus thiamine on function and glycation products of peripheral nerves in diabetic rats. Exp Clin Endocrinol Diabetes. 2001;109(6):330–336. DOI: 10.1055/s-2001-17399.
43. Barulin A.E., Kurushina O.V., Puchkov A.E. Complex treatment of acute non-specific pain in the lower back. Neurology, neuropsychiatry, psychosomatics. 2014;3:38–42 (in Russ.).
44. Apeldoorn A.T., Bosmans J.E., Ostelo R.W. et al. Cost-effectiveness of a classification-based system for sub-acute and chronic low back pain. Eur Spine J. 2012;21:1290–1300. DOI: 10.1007/s00586-011-2144-4.
45. Beneciuk J.M., Bishop M.D., Fritz J.M. et al. The STarT back screening tool and individual psychological measures: evaluation of prognostic capabilities for low back pain clinical outcomes in outpatient physical therapy settings. Phys Ther. 2013;93:321–333. DOI: 10.2522/ptj.20120207.