Takotsubo cardiomyopathy: a clinical case

D.D. Azizova, A.M. Aldabergenova, K.T. Zhumabai, G.B. Kanafina, Zh.R. Turgambayeva  

Astana Medical University, Nur-Sultan, Kazakhstan

Takotsubo cardiomyopathy belongs to the group of heterogeneous diseases. It is a primary acquired stress-induced syndrome resulting from dysfunction of myocardial mid- and apical segments in the setting of resting global left ventricular contractility or hyperkinesis of the basal segments. This cardiomyopathy occurs in 1–2% of all patients with acute coronary syndrome signs, mainly in postmenopausal women without significant atherosclerotic coronary artery lesions. Clinical manifestations are similar to the myocardial infarction symptoms, and therefore, diagnosis establishment is somewhat complicated. Medical treatment commonly includes standard therapy used for myocardial infarction and heart failure since Takotsubo cardiomyopathy is complicated by the occurrence of heart failure in almost half of cases. Therapy duration is 1 to 4 weeks, during which the contractile function of the heart restores in most cases. The prognosis is commonly favorable. The article presents a clinical case of a female patient with Takotsubo cardiomyopathy. This is the first recorded case on the territory of Kazakhstan. The clinical picture, stages of diagnosis and complications in diagnosis establishment are described.

Keywords: Takotsubo cardiomyopathy, apical segmental dysfunction, transient apical hypokinesis, apical ballooning syndrome, stress-induced cardiomyopathy.

For citation: Azizova D.D., Aldabergenova A.M., Zhumabai K.Т. et al. Takotsubo cardiomyopathy: a clinical case. RMJ. 2021;9:36–38.