Rational therapy for vaginal infections is a gynecologist’s choice
M.S. Selikhova, T.I. Kostenko, A.A. Smol’yaninov
Volgograd State Medical University, Volgograd, Russian Federation
Vaginal discharge is the most common reason for referral to a gynecologist. Given the polyetiological nature of vaginal infections, broad-spectrum medications are selected for treatment. Antiseptic solutions (whose efficacy is similar to antibiotics) included in Russian clinical guidelines for obstetrics and gynecology are now more favored. Chlorohexidine is the most studied antiseptic solution with established efficacy in obstetrics and gynecology, whose hallmark is the lack of inhibiting effects on Lactobacilli and local immunity. Combining chlorohexidine and dexpanthenol is one of the most promising therapeutic tools for bacterial vaginosis and vaginal infections. Dexpanthenol stimulates reparation and recovering vaginal and cervical mucosal integrity. This property is crucial for reducing inflammation and preventing recurrences. Recent multicenter randomized and observational study results have demonstrated high efficacy, safety, and good tolerability of combined preparation for vulvovaginitis of different etiologies and vaginal dysbiosis in women of reproductive age, postmenopausal and pregnant women, and while breastfeeding.
Keywords: vaginal dysbiosis, vulvovaginitis, antiseptic, broad-spectrum, Lactobacilli, reparative.
For citation: Selikhova M.S., Kostenko T.I., Smol’yaninov A.A. Rational therapy for vaginal infections is a gynecologist’s choice. Russian Journal of Woman and Child Health. 2022;5(1):41–45 (in Russ.). DOI: 10.32364/2618-8430-2022-5-1-41-45.
Acknowledgements
The technical edition is supported by STADA AG.
About the authors:
Marina S. Selikhova — Dr. Sc. (Med.), Professor, professor of the Department of Obstetrics and Gynecology, Volgograd State Medical University; 1, Pavshikh Bortsov sq., Volgograd, 400131, Russian Federation; ORCID ID 0000-0002-4393-6111.
Tatyana I. Kostenko — C. Sc. (Med.), Associate Professor, associate professor of the Department of Obstetrics and Gynecology, Volgograd State Medical University; 1, Pavshikh Bortsov sq., Volgograd, 400131, Russian Federation; ORCID ID 0000-0001-5203-3400.
Aleksandr A. Smol’yaninov — postgraduate student of the Department of Obstetrics and Gynecology, Volgograd State Medical University; 1, Pavshikh Bortsov sq., Volgograd, 400131, Russian Federation; ORCID ID 0000-0002-4113-0771.
Contact information: Marina S. Selikhova, e-mail: selichovamarina@yandex.ru.
Financial Disclosure: no authors have a financial or property interest in any material or method mentioned.
There is no conflict of interests.
Received 05.11.2021.
Revised 30.11.2021.
Accepted 23.12.2021.
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