Bacterial vaginosis. Possible solutions to the problem

I.Yu. Ilina, Yu.E. Dobrokhotova

Pirogov Russian National Research Medical University, Moscow

The article is devoted to the problem of bacterial vaginosis (BV) which is the main cause of vaginal dysbiosis in women of the reproductive period. The article highlights the features of diagnosis and treatment. Due to the fact that in BV one has to deal with polymicrobial associations, the sheer fact of detecting opportunistic microflora is not informative in the diagnosis of vaginal infections. The ratio of lactobacilli and opportunistic microorganisms is of fundamental importance. Despite the existing treatment algorithms presented in the clinical guidelines and confirmed by many studies, there are still many unresolved issues. This is due to the variety of microorganisms, leading to the BV development, and difficulties in treatment. Special attention is paid to the possibility of using a combined drug for intravaginal administration containing metronidazole 100 mg and miconazole nitrate 100 mg (Ginocaps)  in outpatient gynecological practice. This combined drug is recommended for BV treatment in combination with metronidazole intake. Besides, this drug can be recommended for the treatment of co-infection and in the presence of pathological vaginal discharge in women, especially of a recurrent nature, as well as in the absence of diagnostics to determine the pathogen, since it is effective against anaerobes and yeast-like fungi of the Candida genus.

Keywords: bacterial vaginosis, pathological vaginal discharge, Amsel’s criteria, Nugent’s criteria, metronidazole, miconazole.

For citation: Ilina I.Yu., Dobrokhotova Yu.E. Bacterial vaginosis. Possible solutions to the problem. RMJ. 2020;11:76–78.