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Annular lichen planus, a rare variant of lichen planus

Abstract

DOI: 10.32364/2587-6821-2020-4-10-642-646

I.I. Zakhur 1, S.V. Koshkin1, V.A. Bobro2

1Kirov State Medical University, Kirov, Russian Federation

2Kirov Regional Clinical Dermatovenerological Dispensary, Kirov, Russian Federation

The paper reviews current data on lichen ruber planus, a disease characterized by multifactorial pathogenesis, polymorphic clinical symptoms, severe long recurrent course, and a significant resistance to treatment. In the last decades, a substantial growth in the prevalence of this dermatosis is observed. Moreover, the rate of atypical cases also increases. The most common symptoms at disease onset are a generalized rash, severe itching, and malaise. Many patients present with acute clinical signs. Patients with the different forms of the disease (in particular, those with oral lichen planus) report on the significant reduction in the quality of life. The authors describe the specificity of clinical polymorphism, the variability of clinical manifestations and HLA system in annular lichen planus. The aim of this paper is to summarize currently available data considering the diversity of clinical variants which are required for the understanding of the pathogenesis to improve th e diagnosis in difficult cases and to control its course. The authors also address a case study of annular lichen planus in a 63-year-old woman.

Keywords: lichen ruber planus, dermatosis, histopathology, HLA system.

For citation: Zakhur I.I., Koshkin S.V., Bobro V.A. Annular lichen planus, a rare variant of lichen planus. Russian Medical Inquiry. 2020;4(10):642–646. DOI: 10.32364/2587-6821-2020-4-10-642-646.

About the authors:

Irina I. Zakhur — postgraduate student of the Department of Dermatovenerology & Cosmetology, Kirov State Medical University, 112, Karl Marx str., Kirov, 610027, Russian Federation; ORCID iD 0000-0002-1495-4038.

Sergey V. Koshkin — Doct. of Sci. (Med.), Professor, Head of the Department of Dermatovenerology & Cosmetology, Kirov State Medical University, 112, Karl Marx str., Kirov, 610027, Russian Federation; ORCID iD 0000-0002-6220-8304.

Varvara A. Bobro — dermatovenerologist, Kirov Regional Clinical Dermatovenerological Dispensary, 2A, Semashko str., Kirov, 610030, Russian Federation; ORCID iD 0000-0003-2306-1423.

Contact information: Sergey V. Koshkin, e-mail: koshkin_sergei@mail.ru. Financial Disclosure: no authors have a financial or property interest in any material or method mentioned. There is no conflict of interests. Received 15.05.2020, revised 22.06.2020, accepted 07.07.2020.

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