Giant basal cell carcinoma (case report)
DOI: 10.32364/2587-6821-2023-7-6-7
Yu.N. Grekova, N.V. Zilberberg, O.G. Rimar
Ural Research Institute of Dermatovenereology and Immunopathology, Yekaterinburg, Russian Federation
Basal cell skin cancer, or basal cell carcinoma (BCC), is the most common malignant tumor originating from skin keratinocytes or hair follicles. Giant BCCs are malignant skin neoplasms sized more than 5 cm with a greater tendency to invasion and metastasis than "standard" BCCs (sized less than 5 cm). Two or more foci in one person at the same time rarely occur. This paper describes a 69-year-old woman with skin lesions affecting the left scapula sized 20×10 cm and xiphoid process sized 7×4.5 cm that have existed for more than 15 years. During this period, the patient received various treatments with temporary insignificant improvement. Dermoscopy of the skin lesion of the scapula revealed pathological tree-like and tortuous vessels, homogeneous white and red zones, and ulcerations. Dermoscopy of skin lesion of the xiphoid process was uninformative because of rough surface hemorrhagic crusts. Cytology identified complexes of basaloid cells with atypia. Pathomorphologically, both tumors belonged to nodular BCC. For additional examination and treatment decisions, the patient was referred to the regional oncological dispensary.
Keywords: skin cancer, giant basal cell carcinoma, dermoscopy, pathomorphological examination, nodular type.
For citation: Grekova Yu.N., Zilberberg N.V., Rimar O.G. Giant basal cell carcinoma (case report). Russian Medical Inquiry. 2023;7(6):383–386 (in Russ.). DOI: 10.32364/2587-6821-2023-7-6-7.
About the authors:
Yuliya N. Grekova — Dr. Sc. (Med.), leading researcher of the Department of Syphilis and Sexually Transmitted Infections, Ural Research Institute of Dermatovenereology and Immunopathology; 8, Shcherbakov str., Yekaterinburg, 620076, Russian Federation; ORCID iD 0000-0001-7345-3068.
Natal'ya V. Zilberberg — Dr. Sc. (Med.), Professor, Deputy Director for Research, Ural Research Institute of Dermatovenereology and Immunopathology; 8, Shcherbakov str., Yekaterinburg, 620076, Russian Federation; ORCID iD 0000-0002-7407-7575.
Olga G. Rimar — junior researcher of the Scientific Experimental Division of the Pathomorphological Group, Ural Research Institute of Dermatovenereology and Immunopathology; 8, Shcherbakov str., Yekaterinburg, 620076, Russian Federation; ORCID iD 0000-0001-8597-9630.
Contact information: Yuliya N. Grekova, e-mail: kjn@mail.ru.
Financial Disclosure: no authors have a financial or property interest in any material or method mentioned.
There is no conflict of interest.
Received 03.03.2023.
Revised 29.03.2023.
Accepted 21.04.2023.
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